Dpb11 may function with RPA and DNA to initiate DNA replication

Dpb11 is required for the initiation of DNA replication in budding yeast. We found that Dpb11 binds tightly to single-stranded DNA (ssDNA) or branched DNA structures, while its human homolog, TopBP1, binds tightly to branched-DNA structures. We also found that Dpb11 binds stably to CDK-phosphorylate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Bruck, Irina, Dhingra, Nalini, Martinez, Matthew P., Kaplan, Daniel L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415106/
https://ncbi.nlm.nih.gov/pubmed/28467467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177147
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