Sphingosine Kinase 1 Isoform-Specific Interactions in Breast Cancer

Sphingosine kinase 1 (SK1) is a signaling enzyme that catalyzes the formation of sphingosine-1-phosphate. Overexpression of SK1 is causally associated with breast cancer progression and resistance to therapy. SK1 inhibitors are currently being investigated as promising breast cancer therapies. Two m...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Yagoub, Daniel, Wilkins, Marc R., Lay, Angelina J., Kaczorowski, Dominik C., Hatoum, Diana, Bajan, Sarah, Hutvagner, Gyorgy, Lai, Jack H., Wu, Wengen, Martiniello-Wilks, Rosetta, Xia, Pu, McGowan, Eileen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414788/
https://ncbi.nlm.nih.gov/pubmed/25216046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1423
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