New Insight Into Metformin Action: Regulation of ChREBP and FOXO1 Activities in Endothelial Cells

Metformin has been considered a potential adjunctive therapy in treating poorly controlled type 1 diabetes with obesity and insulin resistance, owing to its potent effects on improving insulin sensitivity. However, the underlying mechanism of metformin's vascular protective effects remains obsc...

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Publicat a:Mol Endocrinol
Autors principals: Li, Xiaoyu, Kover, Karen L., Heruth, Daniel P., Watkins, Dara J., Moore, Wayne V., Jackson, Kathyrin, Zang, Mengwei, Clements, Mark A., Yan, Yun
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414702/
https://ncbi.nlm.nih.gov/pubmed/26147751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/ME.2015-1090
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