Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain.

We have isolated a common insertion site, Wnt-3, for proviruses of the mouse mammary tumor virus (MMTV). Of mammary tumors induced by the GR variant of MMTV, 5% contains a provirus at Wnt-3, which is located on mouse chromosome 11. The gene is transcribed into a 3.8-kilobase (kb) mRNA in tumors with...

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Autores principales: Roelink, H, Wagenaar, E, Lopes da Silva, S, Nusse, R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC54147/
https://ncbi.nlm.nih.gov/pubmed/2162045
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