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15-Deoxy-Δ(12,14)-prostaglandin J(2) Exerts Antioxidant Effects While Exacerbating Inflammation in Mice Subjected to Ureteral Obstruction

Urinary obstruction is associated with inflammation and oxidative stress, leading to renal dysfunction. Previous studies have shown that 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) has both antioxidant and anti-inflammatory effects. Using a unilateral ureteral obstruction (UUO) mouse model, we...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mediators Inflamm
Prif Awduron: Nilsson, Line, Palm, Fredrik, Nørregaard, Rikke
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414590/
https://ncbi.nlm.nih.gov/pubmed/28503033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3924912
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