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15-Deoxy-Δ(12,14)-prostaglandin J(2) Exerts Antioxidant Effects While Exacerbating Inflammation in Mice Subjected to Ureteral Obstruction

Urinary obstruction is associated with inflammation and oxidative stress, leading to renal dysfunction. Previous studies have shown that 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) has both antioxidant and anti-inflammatory effects. Using a unilateral ureteral obstruction (UUO) mouse model, we...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Nilsson, Line, Palm, Fredrik, Nørregaard, Rikke
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414590/
https://ncbi.nlm.nih.gov/pubmed/28503033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3924912
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