Tetrahydrobiopterin activates brown adipose tissue and regulates systemic energy metabolism

Brown adipose tissue (BAT) is a central organ that acts to increase energy expenditure; its regulatory factors could be clinically useful in the treatment of obesity. Tetrahydrobiopterin (BH4) is an essential cofactor of tyrosine hydroxylase and nitric oxide synthase (NOS). Although BH4 regulates th...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Oguri, Yasuo, Fujita, Yoshihito, Abudukadier, Abulizi, Ohashi, Akiko, Goto, Tsuyoshi, Furuya, Futoshi, Obara, Akio, Fukushima, Toru, Matsuo, Naomi, Kim, Minji, Hosokawa, Masaya, Kawada, Teruo, Hasegawa, Hiroyuki, Inagaki, Nobuya
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414566/
https://ncbi.nlm.nih.gov/pubmed/28469071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91981
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