Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis

Fibrotic lung disease, most notably idiopathic pulmonary fibrosis (IPF), is thought to result from aberrant wound-healing responses to repetitive lung injury. Increased vascular permeability is a cardinal response to tissue injury, but whether it is mechanistically linked to lung fibrosis is unknown...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Shea, Barry S., Probst, Clemens K., Brazee, Patricia L., Rotile, Nicholas J., Blasi, Francesco, Weinreb, Paul H., Black, Katharine E., Sosnovik, David E., Van Cott, Elizabeth M., Violette, Shelia M., Caravan, Peter, Tager, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414562/
https://ncbi.nlm.nih.gov/pubmed/28469072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86608
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