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Stat3 regulates desmoglein 3 transcription in epithelial keratinocytes
Pemphigus vulgaris (PV) is an epithelial blistering disease caused by autoantibodies to the desmosomal cadherin desmoglein 3 (DSG3). Glucocorticoids improve disease within days by increasing DSG3 gene transcription, although the mechanism for this observation remains unknown. Here, we show that DSG3...
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Publicado no: | JCI Insight |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5414550/ https://ncbi.nlm.nih.gov/pubmed/28469076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92253 |
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