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Determinants of VH1-46 cross-reactivity to pemphigus vulgaris autoantigen desmoglein 3 and rotavirus antigen VP6(,)

Shared VH1-46 gene usage has been described in B cells reacting to desmoglein 3 (Dsg3) in the autoimmune disease pemphigus vulgaris (PV), as well as B cells responding to rotavirus capsid protein VP6. In both diseases, VH1-46 B cells bearing few to no somatic mutations can recognize the disease anti...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Cho, Michael Jeffrey, Ellebrecht, Christoph T., Hammers, Christoph M., Mukherjee, Eric M., Sapparapu, Gopal, Boudreaux, Crystal E., McDonald, Sarah M., Crowe, James E., Payne, Aimee S.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976025/
https://ncbi.nlm.nih.gov/pubmed/27402694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600567
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