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An intermolecular FRET sensor detects the dynamics of T cell receptor clustering
Clustering of the T-cell receptor (TCR) is thought to initiate downstream signalling. However, the detection of protein clustering with high spatial and temporal resolution remains challenging. Here we establish a Förster resonance energy transfer (FRET) sensor, named CliF, which reports intermolecu...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5414349/ https://ncbi.nlm.nih.gov/pubmed/28452360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15100 |
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