KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling

Human colorectal cancer stem cells (CSCs) are tumour initiating cells that can self-renew and are highly tumorigenic and chemoresistant. While genetic mutations associated with human colorectal cancer development are well-known, little is known about how and whether epigenetic factors specifically c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Li, Jiong, Yu, Bo, Deng, Peng, Cheng, Yingduan, Yu, Yongxin, Kevork, Kareena, Ramadoss, Sivakumar, Ding, Xiangming, Li, Xinmin, Wang, Cun-Yu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414094/
https://ncbi.nlm.nih.gov/pubmed/28440295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15146
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