Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis

Chlamydia trachomatis remains a leading cause of bacterial sexually transmitted infections and preventable blindness worldwide. There are, however, limited in vitro models to study the role of host genetics in the response of macrophages to this obligate human pathogen. Here, we describe an approach...

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Publicado en:Nat Commun
Main Authors: Yeung, Amy T. Y., Hale, Christine, Lee, Amy H., Gill, Erin E., Bushell, Wendy, Parry-Smith, David, Goulding, David, Pickard, Derek, Roumeliotis, Theodoros, Choudhary, Jyoti, Thomson, Nick, Skarnes, William C., Dougan, Gordon, Hancock, Robert E. W.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414054/
https://ncbi.nlm.nih.gov/pubmed/28440293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15013
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