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Impact of mixed xenogeneic porcine hematopoietic chimerism on human NK cell recognition in a humanized mouse model

Mixed chimerism is a promising approach to inducing allograft and xenograft tolerance. Mixed allogeneic and xenogeneic chimerism in mouse models induced specific tolerance and global hyporesponsiveness, respectively, of host mouse NK cells. In this study, we investigated whether pig/human mixed chim...

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Foilsithe in:Am J Transplant
Main Authors: Li, Hao Wei, Vishwasrao, Paresh, Hölzl, Markus A., Chen, Stephanie, Choi, Goda, Zhao, Guiling, Sykes, Megan
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414033/
https://ncbi.nlm.nih.gov/pubmed/27401926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13957
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