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Impact of mixed xenogeneic porcine hematopoietic chimerism on human NK cell recognition in a humanized mouse model

Mixed chimerism is a promising approach to inducing allograft and xenograft tolerance. Mixed allogeneic and xenogeneic chimerism in mouse models induced specific tolerance and global hyporesponsiveness, respectively, of host mouse NK cells. In this study, we investigated whether pig/human mixed chim...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Li, Hao Wei, Vishwasrao, Paresh, Hölzl, Markus A., Chen, Stephanie, Choi, Goda, Zhao, Guiling, Sykes, Megan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414033/
https://ncbi.nlm.nih.gov/pubmed/27401926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13957
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