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Impact of mixed xenogeneic porcine hematopoietic chimerism on human NK cell recognition in a humanized mouse model

Mixed chimerism is a promising approach to inducing allograft and xenograft tolerance. Mixed allogeneic and xenogeneic chimerism in mouse models induced specific tolerance and global hyporesponsiveness, respectively, of host mouse NK cells. In this study, we investigated whether pig/human mixed chim...

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Podrobná bibliografie
Vydáno v:Am J Transplant
Hlavní autoři: Li, Hao Wei, Vishwasrao, Paresh, Hölzl, Markus A., Chen, Stephanie, Choi, Goda, Zhao, Guiling, Sykes, Megan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414033/
https://ncbi.nlm.nih.gov/pubmed/27401926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13957
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