טוען...
Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine Exert Inverse Selective Pressure on Plasmodium Falciparum Drug Sensitivity-Associated Haplotypes in Uganda
BACKGROUND: Altered sensitivity to multiple antimalarial drugs is mediated by polymorphisms in pfmdr1, which encodes the Plasmodium falciparum multidrug resistance transporter. In Africa the N86Y and D1246Y polymorphisms have been shown to be selected by treatment, with artemether-lumefantrine (AL)...
שמור ב:
הוצא לאור ב: | Open Forum Infect Dis |
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Main Authors: | , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Oxford University Press
2016
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5413987/ https://ncbi.nlm.nih.gov/pubmed/28480232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofw229 |
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