T follicular helper and T follicular regulatory cells have different TCR specificity

Immunization leads to the formation of germinal centres (GCs) that contain both T follicular helper (Tfh) and T follicular regulatory (Tfr) cells. Whether T-cell receptor (TCR) specificity defines the differential functions of Tfh and Tfr cells is unclear. Here we show that antigen-specific T cells...

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Publicado en:Nat Commun
Main Authors: Maceiras, Ana Raquel, Almeida, Silvia Cristina Paiva, Mariotti-Ferrandiz, Encarnita, Chaara, Wahiba, Jebbawi, Fadi, Six, Adrien, Hori, Shohei, Klatzmann, David, Faro, Jose, Graca, Luis
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413949/
https://ncbi.nlm.nih.gov/pubmed/28429709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15067
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