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An inducible CRISPR-ON system for controllable gene activation in human pluripotent stem cells
Human pluripotent stem cells (hPSCs) are an important system to study early human development, model human diseases, and develop cell replacement therapies. However, genetic manipulation of hPSCs is challenging and a method to simultaneously activate multiple genomic sites in a controllable manner i...
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| Publicado no: | Protein Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5413595/ https://ncbi.nlm.nih.gov/pubmed/28116670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0360-8 |
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