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An inducible CRISPR-ON system for controllable gene activation in human pluripotent stem cells
Human pluripotent stem cells (hPSCs) are an important system to study early human development, model human diseases, and develop cell replacement therapies. However, genetic manipulation of hPSCs is challenging and a method to simultaneously activate multiple genomic sites in a controllable manner i...
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| Vydáno v: | Protein Cell |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Higher Education Press
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5413595/ https://ncbi.nlm.nih.gov/pubmed/28116670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0360-8 |
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