Modulation of Ca(2+) Signaling by Anti-apoptotic B-Cell Lymphoma 2 Proteins at the Endoplasmic Reticulum–Mitochondrial Interface

Mitochondria are important regulators of cell death and cell survival. Mitochondrial Ca(2+) levels are critically involved in both of these processes. On the one hand, excessive mitochondrial Ca(2+) leads to Ca(2+)-induced mitochondrial outer membrane permeabilization and thus apoptosis. On the othe...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autores principales: Vervliet, Tim, Clerix, Eva, Seitaj, Bruno, Ivanova, Hristina, Monaco, Giovanni, Bultynck, Geert
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413508/
https://ncbi.nlm.nih.gov/pubmed/28516063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2017.00075
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