Genomic and epigenomic heterogeneity of hepatocellular carcinoma

Understanding the intratumoral heterogeneity of hepatocellular carcinoma (HCC) is instructive for developing personalized therapy and identifying molecular biomarkers. Here we applied whole-exome sequencing to 69 samples from 11 patients to resolve the genetic architecture of subclonal diversificati...

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Vydáno v:Cancer Res
Hlavní autoři: Lin, De-Chen, Mayakonda, Anand, Dinh, Huy Q., Huang, Pinbo, Lin, Lehang, Liu, Xiaoping, Ding, Ling-wen, Wang, Jie, Berman, Benjamin P., Song, Er-Wei, Yin, Dong, Koeffler, H. Phillip
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413372/
https://ncbi.nlm.nih.gov/pubmed/28302680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2822
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