MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer

BACKGROUND: Mucin1 (MUC1), a glycoprotein associated with chemoresistance and an aggressive cancer phenotype, is aberrantly overexpressed in triple-negative breast cancer (TNBC). Recent studies suggest that MUC1 plays a role in modulating cancer cell metabolism and thereby supports tumor growth. Her...

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Bibliographic Details
Published in:PLoS One
Main Authors: Goode, Gennifer, Gunda, Venugopal, Chaika, Nina V., Purohit, Vinee, Yu, Fang, Singh, Pankaj K.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413086/
https://ncbi.nlm.nih.gov/pubmed/28464016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176820
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