Markers of Islet Endothelial Dysfunction Occur in Male B6.BKS(D)-Lepr(db)/J Mice and May Contribute to Reduced Insulin Release

Islet endothelial cells produce paracrine factors that support β-cell function and growth. Endothelial dysfunction underlies diabetic microvascular complications; thus, we hypothesized that in diabetes, islet endothelial cells become dysfunctional, which may contribute to β-cell secretory dysfunctio...

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Détails bibliographiques
Publié dans:Endocrinology
Auteurs principaux: Hogan, Meghan F., Liu, Amy W., Peters, Michael J., Willard, Joshua R., Rabbani, Zaheen, Bartholomew, Erik C., Ottley, Adam, Hull, Rebecca L.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2016
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413084/
https://ncbi.nlm.nih.gov/pubmed/27870582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1393
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