Processing of thyrotropin-releasing hormone prohormone (pro-TRH) generates a biologically active peptide, prepro-TRH-(160-169), which regulates TRH-induced thyrotropin secretion.

Rat thyrotropin-releasing hormone (TRH) prohormone contains five copies of the TRH progenitor sequence Gln-His-Pro-Gly linked together by connecting sequences whose biological activity is unknown. Both the predicted connecting peptide prepro-TRH-(160-169) (Ps4) and TRH are predominant storage forms...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Bulant, M, Roussel, J P, Astier, H, Nicolas, P, Vaudry, H
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54130/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2162041/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4439
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