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Engineered ligand‐based VEGFR antagonists with increased receptor binding affinity more effectively inhibit angiogenesis
Pathologic angiogenesis is mediated by the coordinated action of the vascular endothelial growth factor (VEGF)/vascular endothelial growth factor receptor 2 (VEGFR2) signaling axis, along with crosstalk contributed by other receptors, notably α(v)β(3) integrin. We build on earlier work demonstrating...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Bioeng Transl Med |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5412928/ https://ncbi.nlm.nih.gov/pubmed/28516164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10051 |
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