In‐Cell Activation of Organo‐Osmium(II) Anticancer Complexes

The family of iodido Os(II) arene phenylazopyridine complexes [Os(η(6)‐p‐cym)(5‐R(1)‐pyridylazo‐4‐R(2)‐phenyl))I](+) (where p‐cym=para‐cymene) exhibit potent sub‐micromolar antiproliferative activity towards human cancer cells and are active in vivo. Their chemical behavior is distinct from that of...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Needham, Russell J., Sanchez‐Cano, Carlos, Zhang, Xin, Romero‐Canelón, Isolda, Habtemariam, Abraha, Cooper, Margaret S., Meszaros, Levente, Clarkson, Guy J., Blower, Philip J., Sadler, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412917/
https://ncbi.nlm.nih.gov/pubmed/28000997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201610290
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