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Synchrotron X‐Ray Fluorescence Nanoprobe Reveals Target Sites for Organo‐Osmium Complex in Human Ovarian Cancer Cells

A variety of transition metal complexes exhibit anticancer activity, but their target sites in cells need to be identified and mechanisms of action elucidated. Here, it was found that the sub‐cellular distribution of [Os(η(6)‐p‐cym)(Azpy‐NMe(2))I](+) (p‐cym=p‐cymene, Azpy‐NMe(2)=2‐(p‐[dimethylamino]...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Sanchez‐Cano, Carlos, Romero‐Canelón, Isolda, Yang, Yang, Hands‐Portman, Ian J., Bohic, Sylvain, Cloetens, Peter, Sadler, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412901/
https://ncbi.nlm.nih.gov/pubmed/28012260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201605911
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