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The phosphorylation status of T522 modulates tissue‐specific functions of SIRT1 in energy metabolism in mice
SIRT1, the most conserved mammalian NAD (+)‐dependent protein deacetylase, is an important metabolic regulator. However, the mechanisms by which SIRT1 is regulated in vivo remain unclear. Here, we report that phosphorylation modification of T522 on SIRT1 is crucial for tissue‐specific regulation of...
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| Foilsithe in: | EMBO Rep |
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| Main Authors: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
John Wiley and Sons Inc.
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5412809/ https://ncbi.nlm.nih.gov/pubmed/28364022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643803 |
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