Niacin ameliorates ulcerative colitis via prostaglandin D(2)‐mediated D prostanoid receptor 1 activation

Niacin, as an antidyslipidemic drug, elicits a strong flushing response by release of prostaglandin (PG) D(2). However, whether niacin is beneficial for inflammatory bowel disease (IBD) remains unclear. Here, we observed niacin administration‐enhanced PGD(2) production in colon tissues in dextran su...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Li, Juanjuan, Kong, Deping, Wang, Qi, Wu, Wei, Tang, Yanping, Bai, Tingting, Guo, Liang, Wei, Lumin, Zhang, Qianqian, Yu, Yu, Qian, Yuting, Zuo, Shengkai, Liu, Guizhu, Liu, Qian, Wu, Sheng, Zang, Yi, Zhu, Qian, Jia, Daile, Wang, Yuanyang, Yao, Weiyan, Ji, Yong, Yin, Huiyong, Nakamura, Masataka, Lazarus, Michael, Breyer, Richard M, Wang, Lifu, Yu, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412792/
https://ncbi.nlm.nih.gov/pubmed/28341703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606987
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