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Classical and Novel TSPO Ligands for the Mitochondrial TSPO Can Modulate Nuclear Gene Expression: Implications for Mitochondrial Retrograde Signaling

It is known that knockdown of the mitochondrial 18 kDa translocator protein (TSPO) as well as TSPO ligands modulate various functions, including functions related to cancer. To study the ability of TSPO to regulate gene expression regarding such functions, we applied microarray analysis of gene expr...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Yasin, Nasra, Veenman, Leo, Singh, Sukhdev, Azrad, Maya, Bode, Julia, Vainshtein, Alex, Caballero, Beatriz, Marek, Ilan, Gavish, Moshe
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412370/
https://ncbi.nlm.nih.gov/pubmed/28387723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18040786
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