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Dysregulated IER3 Expression is Associated with Enhanced Apoptosis in Titin-Based Dilated Cardiomyopathy

Apoptosis (type I programmed cell death) of cardiomyocytes is a major process that plays a role in the progression of heart failure. The early response gene IER3 regulates apoptosis in a wide variety of cells and organs. However, its role in heart failure is largely unknown. Here, we investigate the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zhou, Qifeng, Hahn, Julia Kelley, Neupane, Balram, Aidery, Parwez, Labeit, Siegfried, Gawaz, Meinrad, Gramlich, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412309/
https://ncbi.nlm.nih.gov/pubmed/28353642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18040723
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