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An in vivo gain-of-function screen identifies the Williams-Beuren Syndrome gene GTF2IRD1 as a mammary tumor promoter
The broad implementation of precision medicine in cancer is impeded by the lack of a complete inventory of the genes involved in tumorigenesis. We screened in vivo ~1,000 genes, that are associated with signaling for positive roles in breast cancer, using lentiviral expression vectors in primary MMT...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5412078/ https://ncbi.nlm.nih.gov/pubmed/27239038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.011 |
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