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An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter

The broad implementation of precision medicine in cancer is impeded by the lack of a complete inventory of the genes involved in tumorigenesis. We performed in vivo screening of ∼1,000 genes that are associated with signaling for positive roles in breast cancer, using lentiviral expression vectors i...

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Main Authors: Yongliang Huo, Timothy Su, Qiuyin Cai, Ian G. Macara
格式: Artigo
語言:Inglês
出版: Elsevier 2016-06-01
叢編:Cell Reports
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2211124716305782
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