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Inhibition of autophagy results in a reversal of taxol resistance in nasopharyngeal carcinoma by enhancing taxol-induced caspase-dependent apoptosis
Drug resistance in nasopharyngeal carcinoma remains a major obstacle of clinical therapy. We found that the taxol-resistant cells demonstrated higher basal levels of autophagy than parental cells, which could be inhibited by 3-MA and Beclin-1-siRNA. We further revealed that inhibition of autophagy e...
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| Publicado no: | Am J Transl Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
e-Century Publishing Corporation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5411941/ https://ncbi.nlm.nih.gov/pubmed/28469798 |
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