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Apogossypolone induces apoptosis and autophagy in nasopharyngeal carcinoma cells in an in vitro and in vivo study

Nasopharyngeal carcinoma (NPC) has a high incidence and mortality rate, particularly in Southern China. Apogossypolone (ApoG2) is a novel derivative of gossypol with antitumor activity and less toxicity. The human NPC CNE-2 cell line was studied in the in vitro model; whilst 4 week-old male nude mic...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Zheng, Ruinian, Chen, Kexu, Zhang, Yu, Huang, Jie, Shi, Fengrong, Wu, Gang, Wang, Senming
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494797/
https://ncbi.nlm.nih.gov/pubmed/28693230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6176
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