Melatonin promoted renal regeneration in folic acid-induced acute kidney injury via inhibiting nucleocytoplasmic translocation of HMGB1 in tubular epithelial cells

Melatonin (N-acetyl-5-methoxytryptamine), a circadian-regulating hormone, has been reported to exert a protective role during acute kidney injury (AKI) induced by renal ischemia-reperfusion injury (I/R). High-mobility group box 1 (HMGB1) is a novel member of the damage-associated molecular pattern (...

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Gepubliceerd in:Am J Transl Res
Hoofdauteurs: Zhu, Fengming, Chong Lee Shin, Octavia LS, Xu, Huzi, Zhao, Zhi, Pei, Guangchang, Hu, Zhizhi, Yang, Juan, Guo, Yanchao, Mou, Jingyi, Sun, Jie, Zhu, Han, Wang, Yuxi, Wang, Meng, Yang, Qian, Liao, Wenhui, Xu, Gang, Zeng, Rui, Yao, Ying
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411918/
https://ncbi.nlm.nih.gov/pubmed/28469775
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