Role of interleukin-10 in the neuroprotective effect of the angiotensin type 2 receptor agonist, compound 21, after ischemia/reperfusion injury

INTRODUCTION: We and others have shown that the angiotensin type 2 (AT2) receptor agonist, compound 21 (C21), provides neuroprotection and enhances recovery in rodent stroke models yet the mechanism involved is not known. Moreover, C21 treatment is associated with an anti-inflammatory response. Here...

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Veröffentlicht in:Eur J Pharmacol
Hauptverfasser: Fouda, Abdelrahman Y, Pillai, Bindu, Dhandapani, Krishnan M., Ergul, Adviye, Fagan, Susan C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411859/
https://ncbi.nlm.nih.gov/pubmed/28192099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2017.02.016
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