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Chemokine Receptor Ccr7 Restricts Fatal West Nile Virus Encephalitis

West Nile virus (WNV) is a mosquito-transmitted flavivirus that can cause debilitating encephalitis. To delineate the mechanisms behind this pathology, we studied Ccr7-deficient mice, which afforded us the capacity to study infection in mice with disrupted peripheral cellular trafficking events. The...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Bardina, Susana V., Brown, Julia A., Michlmayr, Daniela, Hoffman, Kevin W., Sum, Janet, Pletnev, Alexander G., Lira, Sergio A., Lim, Jean K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411599/
https://ncbi.nlm.nih.gov/pubmed/28356527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02409-16
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