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Chemokine Receptor CCR2 is Critical for Monocyte Accumulation and Survival in West Nile Virus Encephalitis

West Nile virus (WNV) is a re-emerging pathogen responsible for outbreaks of fatal meningoencephalitis in humans. Previous studies have suggested a protective role for monocytes in a mouse model of WNV infection, but the molecular mechanisms have remained unclear. Here we show that genetic deficienc...

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Detalhes bibliográficos
Main Authors: Lim, Jean K., Obara, Christopher J., Rivollier, Aymeric, Pletnev, Alexander G., Kelsall, Brian L., Murphy, Philip M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402345/
https://ncbi.nlm.nih.gov/pubmed/21131425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003003
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