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Myeloid derived suppressor cell subset accumulation in renal cell carcinoma parenchyma is associated with intratumoral expression of IL-1β, IL-8, CXCL5 and Mip-1α

PURPOSE: Little is known about the association between MDSC subsets and various chemokines in patients with RCC, or the factors that draw MDSC into tumor parenchyma. EXPERIMENTAL DESIGN: We analyzed PMN-MDSC, M-MDSC and I-MDSC from the parenchyma and peripheral blood of 48 RCC patients, isolated at...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Najjar, Yana G., Rayman, Patricia, Jia, Xuefei, Pavicic, Paul G., Rini, Brian I., Tannenbaum, Charles, Ko, Jennifer, Haywood, Samuel, Cohen, Peter, Hamilton, Thomas, Diaz-Montero, C. Marcela, Finke, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411325/
https://ncbi.nlm.nih.gov/pubmed/27799249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1823
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