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Dynamics of adaptive immunity against phage in bacterial populations

The CRISPR (clustered regularly interspaced short palindromic repeats) mechanism allows bacteria to adaptively defend against phages by acquiring short genomic sequences (spacers) that target specific sequences in the viral genome. We propose a population dynamical model where immunity can be both a...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Bradde, Serena, Vucelja, Marija, Teşileanu, Tiberiu, Balasubramanian, Vijay
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411097/
https://ncbi.nlm.nih.gov/pubmed/28414716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005486
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