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A hybrid deconvolution approach for estimation of in vivo non-displaceable binding for brain PET targets without a reference region

BACKGROUND AND AIM: Estimation of a PET tracer’s non-displaceable distribution volume (V(ND)) is required for quantification of specific binding to its target of interest. V(ND) is generally assumed to be comparable brain-wide and is determined either from a reference region devoid of the target, of...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Zanderigo, Francesca, Mann, J. John, Ogden, R. Todd
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411064/
https://ncbi.nlm.nih.gov/pubmed/28459878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176636
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