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Empirical Bayesian Estimation in Graphical Analysis: a Voxel-Based Approach for the Determination of the Volume of Distribution in PET Studies
INTRODUCTION: Total volume of distribution (V(T)) determined by graphical analysis (GA) of PET data suffers from a noise-dependent bias. Likelihood estimation in GA (LEGA) eliminates this bias at the region of interest level (ROI), but at voxel noise levels, the variance of estimators is high, yield...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896257/ https://ncbi.nlm.nih.gov/pubmed/20447556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.02.004 |
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