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Empirical Bayesian Estimation in Graphical Analysis: a Voxel-Based Approach for the Determination of the Volume of Distribution in PET Studies

INTRODUCTION: Total volume of distribution (V(T)) determined by graphical analysis (GA) of PET data suffers from a noise-dependent bias. Likelihood estimation in GA (LEGA) eliminates this bias at the region of interest level (ROI), but at voxel noise levels, the variance of estimators is high, yield...

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書誌詳細
主要な著者: Zanderigo, Francesca, Ogden, R. Todd, Bertoldo, Alessandra, Cobelli, Claudio, Mann, J. John, Parsey, Ramin V.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896257/
https://ncbi.nlm.nih.gov/pubmed/20447556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.02.004
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