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CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel

Cyclic nucleotide-gated (CNG) and hyperpolarization-activated cyclic nucleotide-regulated (HCN) ion channels play crucial physiological roles in phototransduction, olfaction, and cardiac pace making. These channels are characterized by the presence of a carboxyl-terminal cyclic nucleotide-binding do...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: James, Zachary M., Borst, Andrew J., Haitin, Yoni, Frenz, Brandon, DiMaio, Frank, Zagotta, William N., Veesler, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410850/
https://ncbi.nlm.nih.gov/pubmed/28396445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700248114
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