APC/C(Cdh1)-Rock2 pathway controls dendritic integrity and memory

Disruption of neuronal morphology contributes to the pathology of neurodegenerative disorders such as Alzheimer’s disease (AD). However, the underlying molecular mechanisms are unknown. Here, we show that postnatal deletion of Cdh1, a cofactor of the anaphase-promoting complex/cyclosome (APC/C) ubiq...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Bobo-Jiménez, Verónica, Delgado-Esteban, María, Angibaud, Julie, Sánchez-Morán, Irene, de la Fuente, Antonio, Yajeya, Javier, Nägerl, U. Valentin, Castillo, José, Bolaños, Juan P., Almeida, Angeles
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410848/
https://ncbi.nlm.nih.gov/pubmed/28396402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616024114
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares