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Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity

Narcolepsy is a sleep disorder caused by the loss of orexin (hypocretin)-producing neurons and marked by excessive daytime sleepiness and a sudden weakening of muscle tone, or cataplexy, often triggered by strong emotions. In a mouse model for narcolepsy, we previously demonstrated that serotonin ne...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hasegawa, Emi, Maejima, Takashi, Yoshida, Takayuki, Masseck, Olivia A., Herlitze, Stefan, Yoshioka, Mitsuhiro, Sakurai, Takeshi, Mieda, Michihiro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410844/
https://ncbi.nlm.nih.gov/pubmed/28396432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614552114
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