Proteolytic control of the mitochondrial calcium uniporter complex

The mitochondrial calcium uniporter is a Ca(2+)-activated Ca(2+) channel complex mediating mitochondrial Ca(2+) uptake, a process crucial for Ca(2+) signaling, bioenergetics, and cell death. The uniporter is composed of the pore-forming MCU protein, the gatekeeping MICU1 and MICU2 subunits, and EMRE...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Tsai, Chen-Wei, Wu, Yujiao, Pao, Ping-Chieh, Phillips, Charles B., Williams, Carole, Miller, Christopher, Ranaghan, Matthew, Tsai, Ming-Feng
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410796/
https://ncbi.nlm.nih.gov/pubmed/28396416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702938114
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