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Loss of Elp3 Impairs the Acetylation and Distribution of Connexin-43 in the Developing Cerebral Cortex

The Elongator complex is required for proper development of the cerebral cortex. Interfering with its activity in vivo delays the migration of postmitotic projection neurons, at least through a defective α-tubulin acetylation. However, this complex is already expressed by cortical progenitors where...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Laguesse, Sophie, Close, Pierre, Van Hees, Laura, Chariot, Alain, Malgrange, Brigitte, Nguyen, Laurent
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410572/
https://ncbi.nlm.nih.gov/pubmed/28507509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00122
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