“Back to a false normality”: new intriguing mechanisms of resistance to PARP inhibitors

Several evidences have shown that BRCA mutations increased tumor-cells sensitivity to PARP inhibitors by synthetic lethality leading to an accelerated development of several compounds targeting the PARP enzymes system as anticancer agents for clinical setting. Most of such compounds have been invest...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Incorvaia, Lorena, Passiglia, Francesc, Rizzo, Sergio, Galvano, Antonio, Listȶ, Angela, Barraco, Nadia, Maragliano, Rossella, Calò, Valentina, Natoli, Clara, Ciaccio, Marcello, Bazan, Viviana, Russo, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410353/
https://ncbi.nlm.nih.gov/pubmed/28055979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14409
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados