Synergistic anti-tumor efficacy of sorafenib and fluvastatin in hepatocellular carcinoma

Drug resistance to sorafenib is common in patients with hepatocellular carcinoma(HCC). We examined the effects of a combination of sorafenib and fluvastatin on HCC using in vitro and in vivo models. The dual treatment induced apoptosis and reduced cellular viability in HCC more effectively than eith...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cheng, Yang, Luo, RongCheng, Zheng, Hang, Wang, Biao, Liu, YaHui, Liu, DingLi, Chen, JinZhang, Xu, WanFu, Li, AiMin, Zhu, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410302/
https://ncbi.nlm.nih.gov/pubmed/28423574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15575
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