Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling

Obesity increases cancer risk including breast cancer (BC). However, the direct regulatory mechanisms by which obesity promotes BC progression remain largely unknown. We show that lysophosphatidic acid/protein kinase D1 (LPA/PKD-1)-CD36 signaling is a bona fide breast cancer promoter via stimulating...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Dong, Liuyi, Yuan, Ye, Opansky, Cynthia, Chen, Yiliang, Aguilera-Barrantes, Irene, Wu, Shiyong, Yuan, Rong, Cao, Qi, Cheng, Yee Chung, Sahoo, Daisy, Silverstein, Roy L., Ren, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410244/
https://ncbi.nlm.nih.gov/pubmed/28186980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15123
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